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How Hemoglobin Picks Up and Delivers Oxygen

By: HWC, Views: 5920

All of the cells in our bodies require oxygen (02) for survival and must release carbon dioxide (CO2) as a waste product. The respiratory and circulatory systems work together as delivery systems for these gases. The lungs exchange these gases between the environment and the bloodstream. The bloo...

Hemoglobin's affinity with oxygen - carbon dioxide, temperature and bisphosphoglycerate (BPG)

By: HWC, Views: 6780

• The carbon dioxide gas is temporarily converted to carbonic acid in red blood cells by the enzyme carbonic anhydrase, and then further converted to hydrogen and bicarbonate ions. • The result of increased carbon dioxide is decreased pH causing the Bohr effect. • Elevated carbon dioxid...

Oxygen - hemoglobin dissociation curve & Hemoglobin's affinity with oxygen - acidity

By: HWC, Views: 7286

• The partial pressure of oxygen is a primary factor influencing the degree of saturation of hemoglobin. • The Po2 determines the number of oxygen molecules that can bind or dissociate from hemoglobin. • Blood in vessels coming from the lungs is very high in Po2 so saturation is high. ...

Erythropoietin (EPO)

By: HWC, Views: 6204

■ Secreted by kidney cells when blood oxygen is low. ■ Targets cells in red bone marrow that will become red blood cells. ■ Promotes increased numbers of mature red blood cells. ■ More mature red blood cells carry more oxygen so blood oxygen level is restored to normal.

T cell receptors

By: HWC, Views: 6342

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 6992

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

Cardiac conductile cells

By: HWC, Views: 6884

• In order for the heart to function properly, all of its cells must contract in a specific sequence. This sequence is determined by a pathway known as the conduction system. • Cardiac muscle cells have two attributes that enable the conduction system to work: • Connective. Action pot...

Griffith's experiments

By: HWC, Views: 3783

In the late 1920s, Fred Griffith was attempting to develop a vaccine against a bacterium that causes pneumonia. To find out why two strains of the bacteria differed in their deadliness, he injected mice with four different mixtures. Mice injected with R cells remained healthy. When Griffith ex...

Cell mediated immune response to a viral infection Animation

By: HWC, Views: 2687

Intracellular pathogens are the targets of cell-mediated immune response. The process begins when a virus infects a macrophage. Another macrophage engulfs the same virus or an antigen from it. In both cells, enzymes cleave the viral antigens into small bits. The fragments move to the cell sur...